Vaccines against Covid-19 and pregnancy: a study by the Toulouse University Hospital to enrich knowledge
The Toulouse University Hospital and the Hospices Civils de Lyon are looking for pregnant women volunteers to enrich knowledge on vaccines against Covid-19. Recruitment is open until June.
French clinical data on pregnant women and vaccination against Covid-19 are still too few, even if the two years of the pandemic are beginning to give us some perspective in terms of pharmacovigilance. “We know, for example, that a pregnant woman can be vaccinated at any time during her pregnancy, we also know that a pregnant woman who contracts Covid has a greater risk of developing complications if she is not vaccinated”, describes Isabelle Lacroix, pharmacologist at the Toulouse University Hospital and physician investigator of the COVACPREG study with Dr Judith Cottin. “But in France, for example, between 12 and 15% of pregnancies end in miscarriage and it is difficult to precisely assess the cause. It is therefore to enrich our knowledge of vaccines against Covid in pregnant women that we have launched this prospective and anonymous study. »
Already 1,000 volunteers
COVACPREG offers women over the age of eighteen, pregnant at the time of vaccination, whatever the dose, and whatever the stage of pregnancy, to include themselves online. Those who find out they are pregnant within a month of being vaccinated can also participate.
“To do this, they enter their details online and return a questionnaire on the characteristics of their pregnancy; then are contacted by telephone in the days that follow, specifies Isabelle Lacroix. The objective is to refine the inclusion data. They are asked in particular which vaccine they have received, if they are taking medication, if they have had a medical and gynecological history… ”
After a month, the volunteers adopt a second online questionnaire to measure the possible adverse effects of the vaccine. Finally, they are contacted again one month after the theoretical delivery date to compile post-delivery health data and review the medication follow-up. To date, 1,000 volunteers are taking part and doctors want there to be at least 2,000. Inclusion (1) is open until June 2022.